TargetMol Chemicals

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NVP-BHG712 T6348

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 _M, 1.266 _M and 1.667 _M, respectively.

CAS nr:

940310-85-0

Purity:

98%

Molecular Weight:

503,49

SMILES:

Cc1ccc(cc1Nc1nc(nc2n(C)ncc12)-c1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F

Formula:

C26H20F3N7O

Pathway:

MAPK,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

Raf,Bcr-Abl,Src,Src,Ephrin Receptor,Bcr-Abl,Bcr-Abl