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Bioactivity:
IWR-1, a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
CAS nr:
1127442-82-3
Purity:
98%
Molecular Weight:
409,44
SMILES:
O=C(Nc1cccc2cccnc12)c1ccc(cc1)N1C(=O)[C@H]2[C@@H]3C[C@@H](C=C3)[C@H]2C1=O
Formula:
C25H19N3O3
Pathway:
Stem Cells,Cytoskeletal Signaling
Target:
Wnt/beta-catenin,Wnt/beta-catenin