Bioactivity:

Bosentan is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous

CAS nr:

147536-97-8

Purity:

98%

Molecular Weight:

551,61

SMILES:

CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1c(c(nc(n1)c1ncccn1)OCCO)Oc1ccccc1OC

Formula:

C27H29N5O6S

Pathway:

GPCR/G Protein

Target:

Endothelin Receptor