Bioactivity:

5Z-7-Oxozeaenol, a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.

CAS nr:

253863-19-3

Purity:

98%

Molecular Weight:

362,37

SMILES:

O=C(O[C@@H](C)C/C=C\1)C2=C(O)C=C(OC)C=C2/C=C/C[C@H](O)[C@H](O)C1=O

Formula:

C19H22O7

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Microbiology/Virology,MAPK,MAPK,Tyrosine Kinase/Adaptors,Angiogenesis

Target:

PDGFR,PDGFR,FLT,FLT,VEGFR,VEGFR,Antibiotic,MAPK,MEK,Src,Src