Bioactivity:

Transtinib is an effective and irreversible EGFR tyrosine kinase inhibitor (EGFR-TKI) that is active against L858R/T790M mutated NSCLC cell lines and xenografts.

CAS nr:

1246089-27-9

Purity:

98%

Molecular Weight:

562,04

SMILES:

O=C(NC1=CC2=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)N=CN=C2C=C1OCC)/C=C/[C@H]5NCCC5

Formula:

C30H29ClFN5O3

Pathway:

Target: