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Bioactivity:
PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM) with favorable properties. PF-06462894 did not show any evidence of immune activation in a mouse drug allergy model.
CAS nr:
1622291-66-0
Purity:
98%
Molecular Weight:
329,4
SMILES:
O=C1C=C(OCC2=NC=CC=C2)N=C3COC[C@@H](CC(C)(C)C)N31
Formula:
C18H23N3O3
Pathway:
Target: