Bioactivity:

GSK872 HCl is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).

CAS nr:

T4074L

Purity:

98%

Molecular Weight:

419,94

SMILES:

CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4.Cl

Formula:

C19H18ClN3O2S2

Pathway:

NF-_b,Apoptosis

Target:

RIP kinase,RIP kinase