Bioactivity:

BQ-788 is a potent, selective antagonist of ETB receptor (IC50: 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells), poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells (IC50: 1300 nM).

CAS nr:

173326-37-9

Purity:

98%

Molecular Weight:

641,8

SMILES:

CCCC[C@H](C(O)=O)NC([C@@H](CC1=CN(C(OC)=O)C2=CC=CC=C12)NC([C@H](CC(C)(C)C)NC(N3[C@H](C)CCC[C@@H]3C)=O)=O)=O

Formula:

C34H51N5O7

Pathway:

Others

Target:

Others