Bioactivity:

Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity.�Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAK

CAS nr:

16503-32-5

Purity:

98%

Molecular Weight:

346,41

SMILES:

C/C=C(C)\C(O[C@H]1[C@@]([C@@H]2C)([H])[C@@](OC2=O)([H])C[C@@H](C)[C@@]3([H])[C@]1(C(C=C3)=O)C)=O

Formula:

C20H26O5

Pathway:

JAK/STAT signaling,Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells,Autophagy,Apoptosis,Microbiology/Virology

Target:

STAT,JAK,JAK,JAK,JAK,STAT,Autophagy,Apoptosis,Anti-infection