Bioactivity:

TAK-700 (Orteronel) is a potent and highly selective human 17, 20-lyase inhibitor with IC50 of 38 nM, exhibits >1000-fold selectivity over other CYPs (e.g. 11-hydroxylase and CYP3A4). Phase 3.

CAS nr:

426219-18-3

Purity:

98%

Molecular Weight:

307,35

SMILES:

CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)C3(CCN4C3=CN=C4)O

Formula:

C18H17N3O2

Pathway:

Metabolism

Target:

P450