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Bioactivity:
AMG319 is a potent and selective PI3K_ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
CAS nr:
1608125-21-8
Purity:
98%
Molecular Weight:
385,4
SMILES:
C[C@H](Nc1ncnc2nc[nH]c12)c1cc2ccc(F)cc2nc1-c1ccccn1
Formula:
C21H16FN7
Pathway:
PI3K/Akt/mTOR signaling
Target:
PI3K