Bioactivity:

TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 ﾵM. TG6-129 reduces the expression of COX-2, IL-1_, IL-6, IL-12, IL-23 and TNF-_ induced by the EP2-selective

CAS nr:

1164464-14-5

Purity:

98%

Molecular Weight:

491,57

SMILES:

FC1=CC=C(/C=C/C(NC(NC2=CC=C(S(NC3=NN=C(CC)S3)(=O)=O)C=C2)=S)=O)C=C1

Formula:

C20H18FN5O3S3

Pathway:

Target: