Bioactivity:

JTK-109 is an inhibitor of thumb 1 binding RNA-directed RNA polymerase (NS5B). JTK-109 also inhibits G1b and G3a subgenomic replicons and recombinant enzymes but is 41-fold less active against the G2a replicon.

CAS nr:

480462-62-2

Purity:

98%

Molecular Weight:

674,59

SMILES:

O=C(C1=CC=C2C(N=C(C3=CC=C(OCC4=CC(N5C(CCC5)=O)=CC=C4C6=CC=C(Cl)C=C6)C=C3F)N2C7CCCCC7)=C1)O.[H]Cl

Formula:

C37H34Cl2FN3O4

Pathway:

Target: