TargetMol Chemicals

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CLP257 T14984

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

CLP257 is a selective activator of K+-Cl_ cotransporter KCC2 (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviates hypersensitivity in rats with neuropathic panic and it also modulates plasmalemmal KCC2 pr

CAS nr:

1181081-71-9

Purity:

98%

Molecular Weight:

307,34

SMILES:

O=C1N=C(N2CCCCN2)S/C1=C\C3=CC=C(F)C=C3O

Formula:

C14H14FN3O2S

Pathway:

Membrane transporter/Ion channel

Target:

Potassium Channel