Bioactivity:

Remibrutinib inhibits BTK activity with an IC50 value of 0.023 _M in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment.

CAS nr:

1787294-07-8

Purity:

98%

Molecular Weight:

507,53

SMILES:

CC1=C(C=C(C=C1NC(=O)C2=C(C=C(C=C2)C3CC3)F)F)C4=C(C(=NC=N4)N)OCCN(C)C(=O)C=C

Formula:

C27H27F2N5O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK