Bioactivity:

BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274. It impairs the anchorage-independent growth of KEAP1-mutant cancer cells.

CAS nr:

2444815-73-8

Purity:

98%

Molecular Weight:

506,46

SMILES:

C1CC(CCN(C1)C(=O)C2=CC=C(C=C2)N3CCOCC3)N(CC4=CC=CC=C4)C(=O)CCl.Cl

Formula:

C26H33Cl2N3O3

Pathway:

Others

Target:

Others