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Bioactivity:
CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).
CAS nr:
1818427-07-4
Purity:
98%
Molecular Weight:
430,5
SMILES:
O=C(C1=C2CCC3=C(SN=C3)C2=C(OC4=CC=C(C(NCCOC)=O)N=C4)S1)N
Formula:
C19H18N4O4S2
Pathway:
Cell Cycle/Checkpoint
Target:
CDK