Bioactivity:

Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-�B and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regu

CAS nr:

51551-29-2

Purity:

98%

Molecular Weight:

323,4

SMILES:

C[C@@H]1NC(=O)\C(NC1=O)=C\c1c([nH]c2ccccc12)C(C)(C)C=C

Formula:

C19H21N3O2

Pathway:

Immunology/Inflammation,Apoptosis,GPCR/G Protein,Immunology/Inflammation,Neuroscience,Immunology/Inflammation,NF-_b,MAPK,NF-_b,Immunology/Inflammation,Apoptosis,Neuroscience

Target:

NOS,TNF,Prostaglandin Receptor,Prostaglandin Receptor,COX,COX,I_B/IKK,p38 MAPK,NF-_B,NADPH-oxidase,ASK,Beta Amyloid