Bioactivity:

MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC. It has a Kd of 19_nM for binding affinity to ALK.

CAS nr:

2229036-62-6

Purity:

98%

Molecular Weight:

914,47

SMILES:

CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O

Formula:

C45H52ClN9O8S

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

ALK,ALK