Bioactivity:

PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFR_ and no activity on InsR and PKC.

CAS nr:

260415-63-2

Purity:

98%

Molecular Weight:

443,35

SMILES:

CSc1cccc(Nc2ncc3cc(c(=O)n(C)c3n2)c2c(Cl)cccc2Cl)c1

Formula:

C21H16Cl2N4OS

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Apoptosis,Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling

Target:

Src,Src,Apoptosis,Bcr-Abl,Bcr-Abl,Bcr-Abl