Bioactivity:

BMS986195 is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family (IC50 <1 nM for BTK).

CAS nr:

1912445-55-6

Purity:

98%

Molecular Weight:

370,43

SMILES:

CC#CC(=O)N[C@H]1CCCN(C1)c1c(F)cc(C(N)=O)c2[nH]c(C)c(C)c12

Formula:

C20H23FN4O2

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

BTK,BTK