Bioactivity:

R121919 is an effective small-molecule CRF1 receptor antagonist (Ki: 2 to 5 nM for the CRF1 receptor). It has over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.

CAS nr:

195055-03-9

Purity:

98%

Molecular Weight:

380,53

SMILES:

CCCN(C1=CC(C)=NC2=C(C3=CN=C(N(C)C)C=C3C)C(C)=NN21)CCC

Formula:

C22H32N6

Pathway:

Others

Target:

Others