Bioactivity:

DS-6051b is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of 0.207 nM,0.622 nM,2.28 nM and 0.980 nM, respectively.

CAS nr:

1505515-69-4

Purity:

98%

Molecular Weight:

551,61

SMILES:

OC(=O)CCCCC(O)=O.C[C@@H](N)COc1ccc(cc1)-c1cnc2ccc(N[C@H](C)c3cccc(F)c3)nn12

Formula:

C29H34FN5O5

Pathway:

Immunology/Inflammation,Tyrosine Kinase/Adaptors

Target:

ROS,Trk receptor