Bioactivity:

CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and peptidylglutamyl activities of the proteosome.

CAS nr:

847499-27-8

Purity:

98%

Molecular Weight:

413,28

SMILES:

B([C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)c1cccc(n1)c1ccccc1)(O)O

Formula:

C21H28BN3O5

Pathway:

Proteases/Proteasome,Ubiquitination,NF-_b,Apoptosis

Target:

Proteasome,Proteasome,NF-_B,Apoptosis