Bioactivity:

(+)-Apogossypol is an antagonist of pan-BCL-2. (+)-Apogossypol binds to Mcl-1(Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 ﾵM, respectively).

CAS nr:

66389-74-0

Purity:

98%

Molecular Weight:

494,6

SMILES:

OC1=C2C=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@]1[C@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=CC4=C3O.[S]

Formula:

C28H30O6S

Pathway:

Others

Target:

Others