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Bioactivity:
LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.
CAS nr:
2274819-46-2
Purity:
98%
Molecular Weight:
528,49
SMILES:
Cc1ccc2c(Nc3cccc(OC(F)(F)F)c3)nccc2c1Nc1ncccc1-c1ncnc2c1[nH]cn2
Formula:
C27H19F3N8O
Pathway:
MAPK
Target:
Raf