Bioactivity:

HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with�IC50s of 0.92 nM, 6.6 nM and 9.6 nM for�SIK1, �SIK2�and�SIK3respectively.

CAS nr:

1456858-58-4

Purity:

98%

Molecular Weight:

567,68

SMILES:

CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C

Formula:

C32H37N7O3

Pathway:

PI3K/Akt/mTOR signaling

Target:

SIK