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Bioactivity:
GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).
CAS nr:
1262041-49-5
Purity:
98%
Molecular Weight:
411,46
SMILES:
O=C(Nc1cccc(c1)-c1nncn1C1CC1)c1cc(ccn1)-n1cnc(c1)C1CC1
Formula:
C23H21N7O
Pathway:
Apoptosis,MAPK,Apoptosis
Target:
ASK,MAPK,Apoptosis