API-1 T8969
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
API-1 is a potent inhibitor of Akt. It induces GSK3-dependent, _-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
CAS nr:
36707-00-3
Purity:
98%
Molecular Weight:
337,29
SMILES:
C1=C(C(=O)C2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N)C(=O)N
Formula:
C13H15N5O6
Pathway:
PI3K/Akt/mTOR signaling,Cytoskeletal Signaling
Target:
Akt,Akt