Bioactivity:

PROTAC RAR Degrader-1 comprises a cIAP1 ligand binding group, a linker and a RAR ligand binding group. PROTAC RAR Degrader-1 is an RAR degrader. Maximal RAR degradation at 30 _M concentration in HT1080 cells. Degradation inducers based on cIAP1 are called

CAS nr:

1351169-27-1

Purity:

98%

Molecular Weight:

917,14

SMILES:

O=C(O)C1=CC=C(/C=C/C(C2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)=O)C=C1OCCCNC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC3=CC=CC=C3)=O)=O)=O

Formula:

C51H72N4O11

Pathway:

Others

Target:

Others