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Bioactivity:
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
CAS nr:
607737-87-1
Purity:
98%
Molecular Weight:
286,33
SMILES:
Cc1cccc(n1)-c1[nH]ncc1-c1ccnc2ccccc12
Formula:
C18H14N4
Pathway:
Angiogenesis,Stem Cells,Tyrosine Kinase/Adaptors
Target:
ALK,TGF-beta/Smad,ALK