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Regorafenib T1792

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor (IC50s: 1.5/2.5/4.2/7/13/22 nM for RET/C-RAF/VEGFR2/c-Kit/VEGFR1/PDGFR_).

CAS nr:

755037-03-7

Purity:

98%

Molecular Weight:

482,82

SMILES:

CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1

Formula:

C21H15ClF4N4O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,MAPK,Tyrosine Kinase/Adaptors,Apoptosis,Tyrosine Kinase/Adaptors,Angiogenesis,Autophagy,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR,Raf,c-RET,c-RET,VEGFR,VEGFR,Autophagy,c-Kit