Bioactivity:

LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9 bromodomains (Kd: 99 nM against BRD9).

CAS nr:

1808951-93-0

Purity:

98%

Molecular Weight:

516,05

SMILES:

O=C1N(C2=CC(N(C)C(C=C3C)=O)=C3C=C2)[C@H](C4=CC=C(Cl)C=C4)[C@@H](NS(CC(C)C)(=O)=O)CC1

Formula:

C26H30ClN3O4S

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain