Bioactivity:

SR1664 is a potent and selective PPAR_ inhibitor with potential antidiabetic activity. SR1664 binds to PPAR_ and potently inhibits Cdk5-mediated PPAR_ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR_ agonist activity.

CAS nr:

1338259-05-4

Purity:

98%

Molecular Weight:

547,6

SMILES:

CC(C1=C2C=CC(/C(O)=N/[C@@](C3=CC=C(N(=O)=O)C=C3)([H])C)=C1)=C(N2CC4=CC=C(C5=CC=CC=C5C(O)=O)C=C4)C

Formula:

C33H29N3O5

Pathway:

Metabolism,DNA Damage/DNA Repair

Target:

PPAR,PPAR