Bioactivity:

AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.

CAS nr:

1050500-29-2

Purity:

98%

Molecular Weight:

621,08

SMILES:

Cc1ccc(cc1)S(=O)(=O)O.C=CC(=O)Nc1cc2c(cc1)ncnc2Nc1cc(c(cc1)OCc1cc(ccc1)F)Cl

Formula:

C31H26ClFN4O5S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Tyrosine Kinase/Adaptors

Target:

FLT,FLT,EGFR,EGFR,EGFR