Bioactivity:

Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer

CAS nr:

T26817

Purity:

98%

Molecular Weight:

469,44

SMILES:

O=C1C=CC(C2=NC(S(=O)(C)=O)=NC(C(F)(F)F)=C2)=CN1CC3=CC=C(OC)C(OC)=C3

Formula:

C20H18F3N3O5S

Pathway:

Target: