Bioactivity:

ENMD-119 is a 2-methoxyestradiol analog with antiproliferative and antiangiogenic activity. It is suitable for inhibiting HIF-1_ and STAT3 in human HCC cells.

CAS nr:

864668-87-1

Purity:

98%

Molecular Weight:

311,42

SMILES:

C[C@@]12C=CC[C@@]1([H])[C@]3([H])CCC4=C(C=C(OC)C(C(N)=O)=C4)[C@@]3([H])CC2

Formula:

C20H25NO2

Pathway:

Stem Cells,JAK/STAT signaling,Angiogenesis,Chromatin/Epigenetic

Target:

STAT,STAT,HIF,HIF