Bioactivity:

A 1070722 is a potent and selective GSK-3 inhibitor, with a Ki of 0.6 nM for both GSK-3_ and GSK-3_. It can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in bra

CAS nr:

1384424-80-9

Purity:

98%

Molecular Weight:

362,31

SMILES:

FC(F)(F)C1=NC(NC(NC2=CC=NC3=C2C=CC(OC)=C3)=O)=CC=C1

Formula:

C17H13F3N4O2

Pathway:

Stem Cells,PI3K/Akt/mTOR signaling

Target:

GSK-3,GSK-3