Bioactivity:

Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 _M). Increases secretion of amyoid _-protein (A_) 42, A_40 and A_42 ratio.

CAS nr:

123714-50-1

Purity:

98%

Molecular Weight:

3177,65

SMILES:

Formula:

C142H230N36O44S

Pathway:

Target: