Bioactivity:

ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nM respectively). ARN-3236�Has anti-cancer activity.

CAS nr:

1613710-01-2

Purity:

98%

Molecular Weight:

336,41

SMILES:

COc1ccc(-c2c[nH]c3nccc(-c4ccsc4)c23)c(OC)c1

Formula:

C19H16N2O2S

Pathway:

PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling

Target:

AMPK,SIK