Bioactivity:

Gilteritinib is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong antileukemic and antitumor effects. Gilteritini

CAS nr:

1254053-43-4

Purity:

98%

Molecular Weight:

552,72

SMILES:

CN1CCN(CC1)C2CCN(CC2)c3ccc(cc3OC)Nc5nc(NC4CCOCC4)c(CC)nc5C(N)=O

Formula:

C29H44N8O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors

Target:

FLT,FLT,c-Kit,TAM Receptor