Product info:

This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.

Alternative names:

CYCS; CYC; HCS; THC4; cytochrome c

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Mitochondrion intermembrane space

Isotype:

IgG

Immunogen:

Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human Cytochrome C (NP_061820.1).

Positive control:

293T, Mouse brain, Mouse kidney, Mouse heart, Rat brain, Rat kidney

AA Sequence:

MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE

Purification:

Affinity purification

Molecular weight:

Calculated MW: 11kDa Observed MW: 14KDa

Form:

Liquid

Applications:

WB (rat cells, Mouse N2a, BEL-7402, Homo sapiens, Ctenopharyngodon idellus, Tilapia, Rattus norvegicus, Apocynum venetum leaf, Gallus gallus, Mus musculus) IF (Mouse N2a, Tilapia, Rattus norvegicus) IHC (Gallus gallus)

Dilution:

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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