Product info:

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

Alternative names:

CD106; INCAM-100; VCAM1

Species reactivity:

Human, Mouse, Rat

Host:

Rabbit

Cellular localisation:

Membrane, Single-pass type I membrane protein

Isotype:

IgG

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human VCAM1 (NP_001069.1).

Positive control:

HUVEC, Rat lung

AA Sequence:

NRKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVRSEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVEL

Purification:

Affinity purification

Molecular weight:

Calculated MW: 71kDa/74kDa/81kDa Observed MW: 100-120KDa

Form:

Liquid

Applications:

WB (Homo sapiens, Rattus norvegicus, Mus musculus, Cynoglossus semilaevis) IHC (Mus musculus)

Dilution:

WB 1:1000 - 1:3000 IHC 1:50 - 1:200 IP 1:50 - 1:200

Storage buffer:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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