Product overview:

DDX58 mouse monoclonal antibody, clone LBI6C1

Field of research:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Summary:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]

Alternative names:

RIG-I; RIGI; RLR-1; SGMRT2

Species reactivity:

Human

Host:

Mouse

Target:

DDX58

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human DDX58(NP_055129) produced in HEK293T cell.

Clone:

LBI6C1

Conjugation:

Unconjugated

Gene name:

DExD/H-box helicase 58

Symbol:

DDX58

Pathway:

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:4000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com