Product overview:

DNM1L mouse monoclonal antibody, clone LBI2E7

Field of research:

Endocytosis, Fc gamma R-mediated phagocytosis

Summary:

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008]

Alternative names:

DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV

Species reactivity:

Human, Monkey, Mouse, Rat

Host:

Mouse

Target:

DNM1L

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human DNM1L(NP_036192) produced in HEK293T cell.

Clone:

LBI2E7

Conjugation:

Unconjugated

Gene name:

dynamin 1 like

Symbol:

DNM1L

Pathway:

Endocytosis, Fc gamma R-mediated phagocytosis

Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:200~4000, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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