Product overview:

ADAMTS8 mouse monoclonal antibody, clone LBI2H5

Field of research:

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Summary:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]

Alternative names:

ADAM-TS8; METH2

Species reactivity:

Human

Host:

Mouse

Target:

ADAMTS8

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human ADAMTS8(NP_008968) produced in HEK293T cell.

Clone:

LBI2H5

Conjugation:

Unconjugated

Gene name:

ADAM metallopeptidase with thrombospondin type 1 motif 8

Symbol:

ADAMTS8

Pathway:

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Function:

Druggable Genome, Protease, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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