Product overview:

DEF6 mouse monoclonal antibody, clone LBI3B2

Field of research:

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Summary:

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]). [supplied by OMIM]

Alternative names:

IBP; SLAT; SWAP70L

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DEF6

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human DEF6(NP_071330) produced in HEK293T cell.

Clone:

LBI3B2

Conjugation:

Unconjugated

Gene name:

DEF6 guanine nucleotide exchange factor

Symbol:

DEF6

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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