Product overview:

SRY mouse monoclonal antibody, clone LBI2C7

Field of research:

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Summary:

This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]

Alternative names:

SRXX1; SRXY1; TDF; TDY

Species reactivity:

Human

Host:

Mouse

Target:

SRY

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human SRY(NP_003131) produced in E.coli.

Clone:

LBI2C7

Conjugation:

Unconjugated

Gene name:

sex determining region Y

Symbol:

SRY

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:1000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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