Product overview:

UBE2G2 mouse monoclonal antibody, clone LBI1B10

Field of research:

Parkinson's disease, Ubiquitin mediated proteolysis

Summary:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan

Alternative names:

UBC7

Species reactivity:

Human, Monkey, Mouse, Rat, Dog

Host:

Mouse

Target:

UBE2G2

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human UBE2G2(NP_003334) produced in HEK293T cell.

Clone:

LBI1B10

Conjugation:

Unconjugated

Gene name:

ubiquitin conjugating enzyme E2 G2

Symbol:

UBE2G2

Pathway:

Parkinson's disease, Ubiquitin mediated proteolysis

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:200~2000, IHC 1:150, IF 1:100

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com