Product overview:

TRIM22 mouse monoclonal antibody, clone LBI1D3

Field of research:

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Summary:

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

Alternative names:

GPSTAF50; RNF94; STAF50

Species reactivity:

Human

Host:

Mouse

Target:

TRIM22

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 61-406 of human TRIM22(NP_006065) produced in E.coli.

Clone:

LBI1D3

Conjugation:

Unconjugated

Gene name:

tripartite motif containing 22

Symbol:

TRIM22

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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